1: J Biochem (Tokyo)  1983 Feb;93(2):665-8 

Dynamics of DNA in chromatin and DNA binding mode to core protein.

Ashikawa I, Kinosita K Jr, Ikegami A, Nishimura Y, Tsuboi M, Watanabe K, Iso K.

We have studied the dynamics of DNA in nucleosome core particles and in the
linker region of chromatin using nanosecond fluorescence anisotropy decay
measurements of intercalated ethidium. DNA in the core undergoes torsional
motions to the same extent as the linker DNA in extended chromatin. We therefore
concluded that the binding of DNA to the histone octamer is relatively weak or
limited to a few points; stretches of at least several tens of base pairs exist
which can move as freely as DNA in solution.

PMID: 6841363 [PubMed - indexed for MEDLINE]