Myosin V Is a Left-Handed Spiral Motor
on the Right-Handed Actin Double Helix
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400mM
ATP
4x fast replay
2 revolutions in ~4.4
mm. |
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40mM
ATP
4x fast replay
1 revolutions in ~2
mm. |
Movies:
Upper panel, transmitted images showing the
bead movement; lower panel, fluorescence image showing the fluorescently
labelled actin filament. The bead appears white when it is closer
to, and black when farther from, the observer. Dot on a bead (every 10
frames) indicates the bead carrying myosin V. |
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10mM
ATP
16x fast replay
1.5 revolutions in ~3
mm. |
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M.
Y. Ali et al., Nature Struct. Biol. 9, 464-467 (2002).
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